If you’re looking to spend as much time at home as possible, living near the base is the way to go. There won’t be the wasted time or stress of commuting, and you’ll have much more flexibility to pick up extra flying on short notice to make more money. The downside is that if you’re at a regional, bases can open and close with little notice.
At the majors, living in the base makes sense, especially if it’s a major hub such as Atlanta, Chicago, or Dallas. The downside is that hub-to-hub commuting is usually a nightmare, so you’re essentially stuck in that hub unless you’re willing to move again.
The other major downside to living in the hub is cost. Living in or near any large city is expensive, and some are worse than others. But, for some, the convenience of driving to work is just too good to ignore.
A compromise is to live in easy range of a commute to multiple hubs. If you live in the Midwest, you have doable commutes for Chicago, Dallas, Houston, Atlanta, and the Northeast. As much of an inconvenience as commuting is, you have the option of changing your base to fit your personal needs or wishes. So, if you decide the commute to the Northeast is too hard, you can switch to a different hub. Or, you can easily switch airplanes within your hub.
Commuting is a challenge, but being selective about where you live can make a huge difference in your potential career progression as well as in the amount of money you have left over after expenses. For example, I live in Kentucky. To have the equivalent standard of living in the New Jersey/Pennsylvania area, which would allow me to drive to work, would cost me at least $15,000 a year more than what I spend now (and that’s a conservative guess). But, by staying where I am, I can easily pick up trips to earn extra money, and I can switch bases without doing a hub-to-hub commute. This could let me move up the list of airplanes faster. The downside? More time away from home.
Choosing where to live is always a challenge. If you’re not sure what you want to do long term, then rent first, and, if you’re being honest with yourself, try living in several different cities before making a more permanent choice.